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. 2015 Jul 23;10(7):e0133387. doi: 10.1371/journal.pone.0133387

Fig 3. Col direct control of ap expression in Ap neurons.

Fig 3

(A) Annotation of the Col peak in ap, same representation as in Fig 2A; 35.8 kb of the ap genomic region are shown (Chr2R: 1.593.000–1.628.800); the previously described apC enhancer is represented by a blue box. (B) ap_Col (GFP) expression in the dAp (yellow arrow) and Tv1-Tv4 neurons (white arrow) in stage 15 embryos, ventral view. (C) ap_Colmut expression is severely reduced in dAP neurons and Tv neurons. (D,D’) Close up view of 4 segments of stage 16 embryos, showing the specific overlap between Col (red) and ap_Col (green) in the Tv1 and dAp neurons. (E) all Tv neurons express ap_Col and Eya. (F,G) ap_Colmut expression is lost in dAp and strongly reduced in Tv neurons.