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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Osteoporos Int. 2014 Dec 3;26(3):977–985. doi: 10.1007/s00198-014-2978-9

Figure 2.

Figure 2

Low-turnover CKD associated changes in skeletal collagen crosslinking and tissue hydration. (A) The enzymatic collagen cross-link (deoxypyridinoline, DPD) was significantly higher than normal in low-turnover disease; pyridinoline, PYD was unaffected. (B) Pentosidine, an advanced glycation end product, was found in significantly higher concentrations in CKD bone compared to normal. (C) Pore water fraction was significantly lower and bound water fraction significantly higher in CKD animals compared to normal. * p < 0.05 compared to normal animals.