Table 1. Characteristics of cases with schizophrenia and controls.
Characteristic | Cases | Controls | p-value |
---|---|---|---|
|
|||
n=963 | n=963 | ||
Maternal age, mean (SD) | 28.3 (5.5) | 28.0 (5.1) | 0.20 |
Paternal age, mean (SD) | 31.0 (6.1) | 30.4 (5.7) | 0.03 |
Male, % | 58.1% | 58.1% | 1.00 |
>=1 previous birth (versus 0), % | 62.1% | 62.0% | 0.96 |
Maternal education, % * | |||
Secondary school only | 25.5% | 22.5% | 0.27 |
Vocational degree/secondary school graduate | 57.5% | 57.7% | |
College degree/bachelor university degree | 11.8% | 13.9% | |
Master degree/licenciate degree/PhD | 5.2% | 5.9% | |
Paternal education, % * | |||
Secondary school only | 31.1% | 26.3% | 0.03 |
Vocational degree/secondary school graduate | 51.1% | 57.3% | |
College degree/bachelor university degree | 7.8% | 8.1% | |
Master degree/licenciate degree/PhD | 10.0% | 8.3% | |
Maternal psychiatric disorders | |||
Schizophrenia/non-affective psychosis | 10.2% | 1.8% | <0.0001 |
Affective disorders | 20.9% | 8.4% | <0.0001 |
Any psychiatric disorder | 32.2% | 13.8% | <0.0001 |
Parental psychiatric disorders | |||
Schizophrenia/non-affective psychosis | 16.4% | 3.1% | <0.0001 |
Affective disorders | 30.5% | 13.3% | <0.0001 |
Any psychiatric disorder | 49.6% | 23.3% | <0.0001 |
Gestational age <37 weeks (versus >=37 weeks) * | 7.3% | 5.0% | 0.08 |
Gestational week of blood draw * | |||
Observed completed with estimated, mean (SD) | 11.0 (3.9) | 10.8 (3.9) | 0.38 |
Twin birth (versus singleton) * | 1.9% | 4.4% | 0.002 |
Municipality of birth | |||
Rural | 24.5% | 30.0% | 0.005 |
Semi-urban | 12.1% | 13.7% | |
Urban | 63.5% | 56.3% | |
Province of birth | |||
Eastern Finland | 11.9% | 15.1% | <0.0001 |
Northern Finland | 12.6% | 14.1% | |
Southern Finland | 48.6% | 35.9% | |
Western Finland | 26.9% | 34.9% |
Missing observations: maternal education, n=6; paternal education, n=35; gestational age, n=565; gestational week of blood draw, n=271; plurality, n=6.