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. Author manuscript; available in PMC: 2015 Jul 23.
Published in final edited form as: Cell Rep. 2015 Jul 9;12(3):511–524. doi: 10.1016/j.celrep.2015.06.044

Table 1.

Correlation of gene expression levels in human tumors1.

N-Ras sensitive genes2 N-RAS
K-RAS
r P r P
Down 0.4 2.2 × 10−16 0.0 0.1
Up 0.0 0.9 −0.1 1.5 × 10−6

Notes:

1

n=1,992 tumors (METABRIC database).

2

Median-weighted expression levels of all the genes that are down- or up-regulated when N-RAS expression is repressed (Table S1) were separately analyzed by Pearson correlation to determine whether these correlated with expression of N-RAS and K-RAS. In addition, we similarly analyzed just those six genes validated to be down-regulated upon N-RAS repression (Figure 4A), and found that their expression levels also correlated with those of N-RAS (r = 0.3, P = 2.2 × 10−16), but not with K-RAS.