Table 2.
Left ventricular structure and function of Chronic Renal Insufficiency Cohort participants without chronic heart failure by quartile of Kansas City Cardiomyopathy Questionnaire (KCCQ)*
| Quartile | I (N=779) | II (N=813) | III (N=766) | IV (N=735) | P Value |
|---|---|---|---|---|---|
| KCCQ Score | ≤74.5 | 74.6–91.7 | 91.8–99.0 | >99.0 | |
| LV mass index (g/m2.7) | 55 (14) | 51 (13) | 48 (12) | 46 (12) | <0.001 |
| LVH** | 66% | 51% | 41% | 32% | <0.001 |
| LVEF (%) | 55 (7) | 55 (8) | 55 (7) | 55 (7) | 0.68 |
| LV systolic dysfunction*** | 7% | 10% | 6% | 6% | 0.11 |
| LV diastolic dysfunction**** | 46% | 42% | 40% | 39% | 0.16 |
Note: Mean (Standard Deviation) reported for continuous variables and percentage for categorical variables. P values are obtained using ANOVA or Kruskal-Wallis tests for continuous variables and Chi-square tests for categorical variables.
Left ventricular hypertrophy was defined as LV mass/height2.7 ≥ 47 g/m2.7 for women and ≥ 50 g/m2.7 for men
Systolic dysfunction was defined as ejection fraction <45%.
Diastolic dysfunction was defined as mild to severely abnormal.
Abbreviations: KCCQ: Kansas City Cardiomyopathy Questionnaire; LV: left ventricular; LVH: left ventricular hypertrophy; LVEF: left ventricular ejection fraction.