Fig. 1.

CoQ₁₀ concentrations and oxidative status in plasma and in peripheral blood leukocytes (PBL). Plasma CoQ₁₀ levels at study entry (pre) and following 2-week supplementation (post) (A); % of ubiquinone/total CoQ₁₀ in plasma (B) and in PBL (C). Distribution of data relative to untreated control (ctrl), cells exposed to 100 µM (100) or 200 µM (200) H₂O₂. Data relative to 16 subjects are reported as box plot diagram where the cross (x), the box and the bars represent respectively the median, the 50% and 25% of data distribution.***p<0.01 highly significant, **p<0.05 significant and *p<0.1 approaching significance compared to study entry.