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Effects of WEM on biochemical parameters and pentosidine formation in vivo. WEM was administered to healthy subjects, and the serum pentosidine levels were determined by HPLC. Two tablets (100 mg WEM in total) were administered once a day to healthy women (n = 11) for 12 weeks. The blood glucose (A), HbA1c (B), and pentosidine (C) levels were evaluated every 4 weeks. *p<0.05; **p<0.01 (vs before WEM administration).
