Table 1.
Patient Characteristics by Discharge NOAC and Warfarin Use
Variable | Total Population (n=61655) |
Discharged on NOAC (n=6835) |
Discharged on Warfarin (n=54820) |
p-value |
---|---|---|---|---|
Female sex | 53.1 | 51.8 | 53.3 | 0.016 |
Age | 79 (70–85) | 77 (69–84) | 79 (70–85) | <0.001 |
≥75 | 64.4 | 59.2 | 65.1 | <0.001 |
Race/ethnicity | 0.001 | |||
White | 81.0 | 82.7 | 80.8 | |
Black | 8.7 | 7.3 | 8.9 | |
Hispanic | 4.8 | 4.8 | 4.8 | |
Asian | 2.0 | 1.9 | 2.0 | |
Medical history | ||||
Heart failure | 16.8 | 12.8 | 17.3 | <0.001 |
Hypertension | 79.9 | 79.3 | 79.9 | 0.211 |
Diabetes mellitus | 29.6 | 26.7 | 30.0 | <0.001 |
Prior stroke/TIA | 34.7 | 33.6 | 34.9 | 0.041 |
Prior atrial fibrillation/flutter | 77.0 | 77.1 | 77.0 | 0.911 |
Coronary artery disease | 34.3 | 30.9 | 34.8 | <0.001 |
Peripheral vascular disease | 5.7 | 4.9 | 5.9 | 0.001 |
Carotid stenosis | 4.2 | 4.0 | 4.2 | 0.400 |
Dyslipidemia | 48.5 | 48.6 | 48.5 | 0.957 |
Prosthetic heart valve | 3.9 | 1.4 | 4.2 | <0.001 |
Smoker | 8.2 | 8.0 | 8.2 | 0.528 |
Admission medications | ||||
Antiplatelet therapy | 40.4 | 45.4 | 39.8 | <0.001 |
Anticoagulation | 45.1 | 33.1 | 46.6 | <0.001 |
Admission exam/labs: | ||||
Systolic BP (mmHg) | 150(133–170) | 151(134–172) | 150(133–169) | <0.001 |
Diastolic BP (mmHg) | 80 (69–92) | 80 (70–92) | 80 (69–92) | <0.001 |
Heart rate | 78 (68–92) | 77 (67–91) | 78 (68–92) | 0.001 |
Body mass index | 27.0 (23.6–31.2) | 27.0 (23.8–31.2) | 27.0 (23.6–31.2) | 0.460 |
Hemoglobin A1c | 6.9 (6.2–7.9) | 6.9 (6.2–7.9) | 6.9 (6.2–7.9) | 0.799 |
Creatinine (mg/dL) | 1.0 (0.8–1.3) | 1.0 (0.8–1.2) | 1.0 (0.8–1.3) | <0.001 |
GFR ≥30 mg/dL/1.73m2 | 73.1 | 75.2 | 72.9 | <0.001 |
Total cholesterol | 151(126–179) | 152(128–181) | 150(126–179) | 0.002 |
Median NIH stroke scale | 5 (2–11) | 3 (1–8) | 5 (2–11) | <0.001 |
NIH stroke scale ≥11 | 18.3 | 14.0 | 18.8 | <0.001 |
Insurance status | <0.001 | |||
Medicare | 42.0 | 39.0 | 42.3 | |
Medicaid | 6.2 | 5.4 | 6.3 | |
Insured/HMO | 38.0 | 41.7 | 37.6 | |
Self-pay | 2.1 | 1.4 | 2.2 |
Values represent percentages or medians (interquartile range).
BP indicates blood pressure; GFR, glomerular filtration rate; HMO, health maintenance organization; NIH, National Institute of Health (higher scores on NIH stroke scale indicate greater stroke severity); NOAC, novel oral anticoagulant