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. 2015 Feb 12;3:5. doi: 10.1186/s40635-014-0037-7

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© Reddi et al.; licensee Springer. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Platelet aggregation is inversely correlated with illness severity. There was a significant correlation (p < 0.05) between sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II scores at the time of blood sampling and platelet aggregation induced by (A, C) ADP (r = −0.51 and −0.36) and (B, D) arachidonic acid (r = −0.41 and −0.47) in whole blood taken from patients with septic shock (n = 26). Note: platelet concentration was not significantly lower in the septic shock patients, and there was no correlation between platelet count and either SOFA or APACHE II score (p > 0.05).