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YchF is a member of the HAS-GTPase family. Shown is an alignment of the G3 motif of Ras (gray), YqeH (black), MnmE (yellow), HflX (purple), EHD2 (green), FeoB (pink), Era (red), YsxC (brown), and YlqF (orange) with YchF (cyan). Also shown is GDP·AlF3 and the attacking water molecule (red sphere in line with AlF3) from Ras·RasGap (PDB ID 1WQ1). Alignment was based on the structure of the conserved G1 motif (P-loop). Glncat, catalytic Gln.
