Table 1.
Demographic and neuropsychological characteristics of patient and healthy control groups.
| bvFTD | svPPA | Healthy controls | |
|---|---|---|---|
| General characteristics | |||
| No. | 29 | 15 | 37 |
| Age (yrs) | 64 (7.1) | 65 (6.6) | 63 (7.8) |
| Sex (F:M) | 4:25 | 5:10 | 19:18 |
| Symptom duration (years) | 7.8 (5.3) | 6.2 (1.9) | n/a |
| Neuropsychological assessment | |||
| IQ | |||
| WASI vocab (/80) | 40 (24) | 26 (24)b | 71 (5.3) |
| WASI blocks (/48) | 23 (19) | 29 (19) | 46 (11.2) |
| WASI similarities (/71) | 22 (13) | 16 (16) | 46 (6.0) |
| WASI matrices (/32) | 15 (8.5) | 18 (8.7) | 27 (7.5) |
| NART (/50) | 26 (15) | 26 (16) | 42 (5.9) |
| Episodic memory | |||
| RMT words (/50) | 35 (10) | 33 (6.0) | 48 (2.6) |
| RMT faces (/50) | 35 (8.0) | 34 (8.7) | 43 (4.5) |
| Semantic processing | |||
| BPVS (/150) | 119 (35) | 76 (56)b | 147 (2.1) |
| GNT (/30) | 11 (9.3) | 3.4 (5.8)b | 26 (3.0) |
| Executive function | |||
| D-KEFS Stroop inhibition (sec) | 137 (98)b | 108 (70) | 55 (13) |
| Digit span reverse (/12) | 5.6 (2.9) | 6.1 (3.2) | 7.3 (1.9) |
| Social cognition — TASIT | |||
| Emotion (/14) | 7.1 (2.9) | 5.8 (2.8) | 11 (1.3) |
| Total sarcasm (/24) | 13 (6.7)a | 11 (5.9) | 22 (2.3) |
| Simple sarcasm (/12) | 7.4 (3.5) | 5 (3.5) | 10 (1.4) |
| Paradoxical sarcasm (/12) | 7 (2.9) | 5.7 (2.9) | 11 (1.3) |
| Other skills | |||
| Digit span forward (/12) | 8.8 (1.6) | 6.8 (2.6) | 8.9 (1.7) |
| VOSP (/20) | 16 (3.8) | 15 (3.5) | 18 (1.6) |
Mean (standard deviation) values shown; maximum scores are shown in parentheses after names of tests.
Significant group differences in t tests p < 0.05 relative to the healthy control group are shown in bold.
BPVS, British Picture Vocabulary Scale; bvFTD, behavioural variant frontotemporal dementia; D-KEFS, Delis–Kaplan Executive Function System; GNT, Graded Naming Test; n/a, not available; NART, National Adult Reading Test; RMT, Recognition Memory Test; sec, seconds; svPPA, semantic variant primary progressive aphasia; TASIT, the Awareness of Social Inference Test; VOSP, Visual Object and Space Perception; WASI, Wechsler Abbreviated Scale of Intelligence (see also Supplementary material on-line).
Data from 27 patients (two unable to understand task).
Significant difference between bvFTD and svPPA patients.