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. 2015 Jun 4;38(8):737–747. doi: 10.1007/s40264-015-0302-z

Table 3.

Use of medication conforming to the prescribed dosage and duration

Medication Prx actually taken (n, 100%) Conforming to prx (n) % (95% CI) Not recalled (n) % (95% CI) Not conforming to prx (n) % (95% CI) Lower dose among those not conforming to prx (n) % (95% CI)
Conforming to prescribed dosage
 First trimester
  All medicines 277 218 78.7 (73.9–83.5)a 23 8.3 (5.1—11.6)a 36 13.0 (9.0–17.0)a 34 94.4 (81.9–98.5)b
  All together 76 52 68.4 (58.0–78.9)a 9 11.8 (4.6–19.1)a 14 18.4 (9.7–27.1)a 13 92.9 (68.5–98.7)b
  For chronic diseases together 94 71 75.5 (66.8–84.2)a 9 9.6 (3.6–15.5)a 14 14.9 (7.7–22.1)a 13 92.9 (68.5–98.7)b
  For short–term and occasional use together 107 94 87.9 (81.7–94.0)a 5 4.7 (0.7–8.7)a 8 7.5 (2.5–12.5)a 8 100.0 (67.6–100)b
 Entire pregnancy
  For pregnancy-related symptoms 736 589 80.0 (77.1–82.9)a 56 7.6 (5.7–9.5)a 91 12.4 (10.0–14.7)a 89 97.8 (92.3–99.4)b
  All together 197 147 74.6 (68.5–80.7)a 19 9.6 (5.5–13.8)a 31 15.7 (10.7–20.8)a 30 96.8 (83.8–99.4)b
  For chronic diseases together 273 212 77.7 (72.7–82.6)a 22 8.1 (4.8–11.3)a 39 14.3 (10.1–18.4)a 38 97.4 (86.8–99.5)b
  For short-term and occasional use together 266 230 86.5 (82.4–90.6)a 15 5.6 (2.9–8.4)a 21 7.9 (4.7–11.1)a 21 100.0 (84.5–100)b
Conforming to prescribed duration
 First trimester
  All medicines 277 168 60.6 (54.9–66.4)a 32 11.6 (7.8–15.3)a 77 27.8 (22.5–33.1)a 45 58.4 (47.4–69.4)a
  All together 76 42 55.3 (44.1–66.4)a 10 13.2 (5.6–20.8)a 24 31.6 (21.1–42.0)a 13 54.2 (34.2–74.1)a
  For chronic diseases together 94 55 58.5 (48.6–68.5)a 12 12.8 (6.0–19.5)a 27 28.7 (19.6–37.9)a 12 44.4 (25.7–63.2)a
  For short-term and occasional use together 107 71 66.4 (57.4–75.3)a 10 9.3 (3.8–14.9)a 26 24.3 (16.2–32.4)a 20 76.9 (60.7–93.1)a
 Entire pregnancy
  For pregnancy-related symptoms 736 482 65.5 (62.1–68.9)a 58 7.9 (5.9–9.8)a 196 26.6 (23.4–29.8)a 116 59.2 (52.3–66.1)a
  All together 197 128 65.0 (58.3–71.6)a 20 10.2 (5.9–14.4)a 49 24.9 (18.8–30.9)a 24 49.0 (35.0–63.0)a
  For chronic diseases together 273 171 62.6 (56.9–68.4)a 21 7.7 (4.5–10.9)a 81 29.7 (24.3–35.1)a 45 55.6 (44.7–66.4)a
  For short-term and occasional use together 266 183 68.8 (63.2–74.4)a 17 6.4 (3.5–9.3)a 66 24.8 (19.6–30.0)a 47 71.2 (60.3–82.1)a

Prx prescription

aWald method was applied

bWilson method was applied