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Characterization of a novel miR-15/107 target site within the BRCA1 CDS. The putative binding site for the miR-15/107 group in BRCA1’s CDS was cloned into a luciferase reporter vector along with a corresponding construct containing mutations within the putative miRNA ‘seed’ recognition sites to confirm specificity. ∗P < 0.05, ∗∗P < 0.01 compared to control scramble target sequence by Student’s t-test, n = 3 in each group.
