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. 2015 Jul 24;6:207. doi: 10.3389/fphys.2015.00207

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Copyright © 2015 French, Meisner, Liu, Weckström and Torkkeli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RNAi of combined pTRP and pTRPL reduced ERG significantly after 6 days. Animals received injections containing 4 μg pTRP and 4 μg pTRPL dsRNA. Significant reduction in ERG was seen after 6 days and persisted at 21 days. Upper histograms show mean values at both positions after 21 days treatment with pTRP, pTRPL, and pTRP+pTRPL RNAi. Note that the mean values for pTRPL alone and combined injections were not significantly different. Numbers of recordings were 30 for controls and 14 or 16 for RNAi treatments. Asterisks: ^*p < 0.05, ^***p < 0.001.