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. 2015 Jul 24;8:43. doi: 10.1186/s13041-015-0134-x

Fig. 3.

Fig. 3

Effect of HIV-1 proteins on expression of genes in signaling cascades of synaptic plasticity formation in the hippocampus (a), prefrontal cortex (b), and amygdala (c). Genes involved in calcium signaling and its downstream targets were upregulated in the hippocampus but downregulated in the PFC and amygdala of HIV-1Tg rats compared with F344 control rats. The signaling cascades were drawn by IPA