Table 1.
Effect of the methanolic fraction from Clerodendrum umbellatum leaves aqueous extract on the body weight of mice at pre-infection and on the 65th day post-infection
| Groups | Number of animals (n) | Body weight (g) | Weight gain (%) | p | |
|---|---|---|---|---|---|
| Pre-infection (1st day) | Post-infection (65th day) | ||||
| NIC | 5 | 19.30 ± 0.83 | 24.23 ± 1.05 | 29.53 ± 2.04 (24.28–34.78) | |
| IC | 6 | 23.51 ± 0.90 | 24.31 ± 0.80 | 3.97 ± 3.87 (−5.50–13.44) | <0.001 |
| PZQ | 6 | 21.22 ± 1.04 | 26.00 ± 0.98 | 22.89 ± 2.89 (15.47–30.31) | <0.001 |
| CuF100 | 6 | 23.55 ± 0.55 | 28.14 ± 0.85 | 19.54 ± 2.56 (12.95–26.12) | <0.01 |
| CuF200 | 6 | 21.04 ± 0.89 | 24.94 ± 1.03 | 18.60 ± 1.43 (14.93–22.26) | <0.001 |
| CuF400 | 6 | 22.74 ± 0.51 | 27.07 ± 0.74 | 19.06 ± 1.96 (14.03–24.09) | <0.001 |
Data are expressed as mean ± SEM
Values in brackets represent the 95 % confidence intervals
ANOVA followed by Newman-Keuls multiple comparison test was used to compare on one hand, the infected-untreated mice (IC) to the non-infected mice (NIC), and secondly the infected-treated mice (PZQ, CuF100, CuF200, CuF400) to the infected-untreated mice (IC)