Table 2.
Effect of the methanolic fraction from Clerodendrum umbellatum leaves aqueous extract on the liver and spleen weights of mice on the 65th day post-infection
| Groups | Number of animals (n) | Liver | Spleen | ||||
|---|---|---|---|---|---|---|---|
| Weight (g/100 g) | p | % change | Weight (g/100 g) | p | % change | ||
| NIC | 5 | 6.23 ± 0.34 | 0.50 ± 0.04 | ||||
| IC | 6 | 9.21 ± 0.37 | <0.001 | +47.83 | 1.45 ± 0.17 | <0.001 | +190.00 |
| PZQ | 6 | 6.57 ± 0.46 | <0.001 | −28.66 | 0.43 ± 0.08 | <0.001 | −70.34 |
| CuF100 | 6 | 7.68 ± 0.28 | <0.05 | −16.61 | 0.77 ± 0.08 | <0.001 | −46.90 |
| CuF200 | 6 | 7.90 ± 0.48 | <0.05 | −14.22 | 0.79 ± 0.03 | <0.001 | −45.52 |
| CuF400 | 6 | 5.96 ± 0.47 | <0.001 | −35.29 | 0.66 ± 0.10 | <0.001 | −54.48 |
Data are expressed as mean ± SEM
ANOVA followed by Newman-Keuls multiple comparison test was used to compare on one hand, the infected-untreated mice (IC) to the non-infected mice (NIC), and secondly the infected-treated mice (PZQ, CuF100, CuF200, CuF400) to the infected-untreated mice (IC)