Table 1.
Characteristic | Controls (n = 539) | Patients | P | |||
---|---|---|---|---|---|---|
CAD (n = 525) | IS (n = 540) | P 1 | P 2 | P 3 | ||
Male/female | 374/165 | 383/142 | 390/150 | 0.223 | 0.316 | 0.837 |
Age, years | 63.08 ± 10.76 | 62.27 ± 10.93 | 62.81 ± 12.36 | 0.222 | 0.702 | 0.448 |
Body mass index, kg/m2 | 22.84 ± 3.51 | 23.29 ± 3.33 | 24.75 ± 5.18 | 0.033 | 0.048 | 0.135 |
Systolic blood pressure, mmHg | 133.18 ± 22.95 | 137.00 ± 23.28 | 147.54 ± 21.98 | 0.007 | <0.001 | <0.001 |
Diastolic blood pressure, mmHg | 79.78 ± 13.03 | 81.82 ± 14.13 | 83.71 ± 12.92 | 0.014 | <0.001 | 0.023 |
Pulse pressure, mmHg | 54.38 ± 17.94 | 55.86 ± 18.19 | 63.80 ± 17.98 | 0.185 | <0.001 | <0.001 |
Cigarette smoking, n (%) | 220(40.8) | 233(44.4) | 226(41.9) | 0.264 | 0.757 | 0.421 |
Alcohol consumption, n (%) | 232(43.0) | 220(41.9) | 198(36.7) | 0.710 | 0.035 | 0.090 |
Total cholesterol, mmol/L | 4.70 ± 1.18 | 4.61 ± 1.18 | 4.52 ± 1.15 | 0.217 | 0.014 | 0.232 |
Triglyceride, mmol/L | 1.08(0.81) | 1.21(0.80) | 1.36(0.93) | 0.026 | <0.001 | <0.001 |
HDL-C, mmol/L | 1.48 ± 0.49 | 1.45 ± 0.51 | 1.23 ± 0.40 | 0.267 | <0.001 | <0.001 |
LDL-C, mmol/L | 2.78 ± 0.93 | 2.71 ± 0.90 | 2.68 ± 0.90 | 0.255 | 0.083 | 0.555 |
Apolipoprotein (Apo) AI, g/L | 1.17 ± 0.32 | 1.15 ± 0.29 | 1.02 ± 0.22 | 0.200 | <0.001 | 0.288 |
ApoB, g/L | 0.89 ± 0.23 | 0.90 ± 0.25 | 0.89 ± 0.25 | 0.574 | 0.882 | 0.692 |
ApoAI/ApoB | 1.45 ± 1.76 | 1.37 ± 0.66 | 1.17 ± 0.61 | 0.366 | 0.001 | <0.001 |
Type 2 diabetes mellitus, n (%) | 75(13.9) | 117(22.3) | 116(21.5) | <0.001 | 0.001 | 0.751 |
Hypertension, n (%) | 174(32.3) | 266(50.7) | 289(53.5) | <0.001 | <0.001 | 0.107 |
Hyperlipidemia, n (%) | 198(36.7) | 210(40.0) | 212(39.3) | 0.284 | 0.415 | 0.851 |
Using lipid-lowing drugs, n (%) | 0(0) | 172(32.8) | 150(27.8) | <0.001 | <0.001 | 0.077 |
CAD coronary artery disease, IS ischemic stroke, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
P 1: comparison of CAD and controls; P 2: comparison of IS and controls; P 3: comparison of CAD and IS