Table 1.

Layer-specific left ventrcular strain measurements at rest using CAG as reference for CAD

			Strain values (%)			Differences endo-epic. strain
Study	Indication	CAG	CAD+	CAD-	p-value	CAD+	CAD-	p-value	AUC for CAD+, TLS/GCS (%)
Sarvari [23]	Suspected NSTE-ACS n = 77	CAD+ n = 49	TLS: −14.0 ± 3.3	−19.2 ± 2.2	<0.001	Δ2.4 ± 3.6	Δ5.3 ± 2.1	<0.001	Endocardial: 0.91/0.85
		CAD- n = 28	GCS: −19.3 ± 4.0	- 24.3 ± 3.4	<0.001	Δ2.4 ± 3.7	Δ10.4 ± 3.0	<0.001	Mid-myocardial: 0.91/0.87
			GLS: −15.3 ± 2.2	−19.2 ± 2.2	<0.001	Δ2.4 ± 3.8	Δ5.3 ± 2.1	<0.001	Epicardial: 0.79/0.68

Strain values and differences between andocardial and epicardial strain are presented as mean ± SD

NSTE-ACS Non-ST elevation acute coronary syndrome, CAG Coronary angiography, CAD+ Coronary artery disease, defined as coronary artery stenosis ≥ 50 %, TLS Territorial longitudinal strain, GCS Global circumferential strain, endo endocardial, epic epicardial, AUC Area under the curve for ROC analysis of prediction of CAD being present or not