Table 2.

4 studies on measurements of left ventricular strain at rest to predict CAD+ using coronary angiogram as reference

Study	n	CAG	GLS (%)	p CAD+ vs CAD-	TLS (%)	pCAD+ vs CAD-	AUC for CAD+ (95 % CI)	Cut-off	Sensitivity	Specificity
Montgomery [24]	123	CAD+ n = 56a	−16.8 ± 3,2				GLS 0.72 (0.63-0.82)	- 17.8 %	66 %	76 %
		CAD- n = 67	−19.1 ± 3.4	0.0002			TLS 0.73 (0.62 - 0.83)	- 18.3 %	69 %	70 %
	109	LAD+ n = 35c	−19 ± 2.8		−18.68 ± 3.3
		LAD- n = 74	−17.5 ± 2.7	0.0001	−21.14 ± 3.3
Smedsrud [25]	86	CAD+ n = 43a	−17.7 ± 3.0		−17.9 ± 3.5		GLS 0.68 (0.56-0.79)	−17.4 %	51 %	81 %
		CAD- n = 43	−19.5- ± 2.6	0.003	−20.1 ± 2.9	0.015	TLS 0.67 (0.52-0.82)	n.a.	n.a.	n.a.
Biering-Sørensen [26]	293	CAD+ n = 107b	−17.1 ± 2.5b				GLS 0.68 (0.62-0.74)d	- 18.4 %	74 %	58 %
		CAD- n = 186	- 18.8 ± 2.6	<0.001
Shimoni [27]	97	CAD+ n = 69a	−17.3 ± 2.4		−9.1 ± 3.2		GLS 0.80	−19.7 %	81 %	67 %
		CAD- n = 28	−20.8 ± 2.3	<0.001	−12.9 ± 2.3	<0.001	TLS 0.75	−12.6 %	77 %	68 %

Abbreviations and definitions: CAD+ was defined as ≥ 50 % stenosis ^a in one or more coronary arteries and as ≥ 70 % luminal area reduction^b

LAD: Left anterior desending ^csubset of 109 patients where TLS in the LAD territory was performed. ^d GLS from 12 segments. TLS = territorial longitudinal strain, defined specifically in the text from each study