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. 2015 Jun 25;137(28):9053–9060. doi: 10.1021/jacs.5b03912

Figure 6.

Figure 6

Analysis of the i-motif with a 5′ 25-mer poly dA tail at pH 5.0 with the α-HL nanopore. (A) A 30 s continuous i–t trace. (B) Expanded views of the Type 1′ and 2′ events and graphical models showing the i-motif interactions with α-HL that yield these event types. (C) Comparison of the IM histograms for the i-motif with a 5′-tail (top) and tailless i-motif (bottom) to show that the IM values for the Type 2 and 2′ events are nearly identical. Data were recorded at −120 mV (cis vs trans) at 22 °C in 1.0 M KCl electrolyte solution buffered with 10 mM phosphate and 5 mM citrate at pH 5.0.