Table 1. Summary of minimotifs with SNPs.

Activity	Minimotif Critical Residue SNPs		Missense minimotifs		Minimotifs with SNPs		Total
	N	%	N	%	N	%	N
Acetylation	75	0.396	1214	6.33	2601	13.6	19 179
Di-methylation	10	0.907	73	6.62	172	15.6	1103
Glycosylation	18	0.413	252	5.79	502	11.5	4356
Lipid	1	0.429	14	6.01	26	11.2	233
Mono-methylation	17	1.083	108	6.88	240	15.3	1569
O-glcnac	1	0.424	12	5.08	32	13.6	236
Phosphorylation	900/84a	0.498	13 751	7.6	27 613	15.3	180 891
Proteolysis	140	0.49	1389	4.86	3296	11.5	28 571
Tri-methylation	1	0.571	17	9.71	40	22.9	175
Ubiquitination	79	0.275	1679	5.83	4017	14	28 775
Sumoylation	0	0	27	3.49	86	11.1	773
Dephosphorylation	0	0	6	2.46	29	11.9	244
Nitration	0	0	0	0	3	21.4	14
Total	1243	0.467	18 542	6.97	38 657	14.5	266 119
Distinct SNPs	1044	-	10 961	-	22 846	-	-

^aWe observed 84 polymorphisms encoding Ser-Thr substitutions in minimotifs in addition to the 900 phosphorylation site SNPs.