Table 1. Panel of cell lines used in this study.
Genotype | Parental Cell Line | Markers genes | References |
---|---|---|---|
SMARCAL1−/− | DT40 | hisD, puroR | * |
SMARCAL1Δ30/− | DT40 | hisD | * |
KU70−/− | DT40 | bsrR, puroR | (55) |
BRCA2−/− | DT40 | hygroR, hisD | (46) |
KU70−/−/SMARCAL1Δ30/− | DT40 | hisD, bsrR, puroR | * |
SMARCAL1−/− | TK6-derived TSCER2 and TSCE5 | puroR, hygroR | * T |
LIG4−/−/− | TK6-derived TSCER2 and TSCE5 | puroR, neoR | * C |
RAD54−/− | TK6-derived TSCER2 | puroR, neoR | * T |
SMARCAL1−/−/LIG4−/−/− | TK6-derived TSCE5 | puroR, neoR, hygroR | * T/C |
DNA-PKcs−/− | TK6-derived TSCE5 | neoR, hisD | * C |
SMARCAL1−/−/DNA-PKcs−/− | TK6-derived TSCE5 | neoR, hisD | * T/C |
* = This study; T = TALEN; C = CRISPR.