Table 1.
Anthropometric, spirometric, lung volumes and nocturnal PSG data in the OSA group and non-OSA group for men and women
| Variables | Men (n = 193) | Women (n = 70) | ||||
|---|---|---|---|---|---|---|
| Non-OSA group (n = 87) | OSA group (n = 106) | p-Value | Non-OSA group (n = 35) | OSA group (n = 35) | p-Value | |
| Age, years | 44 ± 8 | 45 ± 10 | 0.605 | 47 ± 9 | 50 ± 9 | 0.091 |
| Height, cm | 172 ± 5.5 | 171 ± 6.3 | 0.269 | 158 ± 5.1 | 157 ± 6.0 | 0.266 |
| Weight, kg | 82 ± 10.4 | 90 ± 14.8 | <0.001 | 74 ± 12.3 | 75 ± 13.5 | 0.698 |
| BMI, kg/m2 | 28.0 ± 3.0 | 30.5 ± 4.2 | <0.001 | 29.7 ± 4.9 | 30.7 ± 5.1 | 0.388 |
| FVC, L | 4.19 ± 0.50 | 4.06 ± 0.62 | 0.117 | 3.07 ± 0.49 | 2.83 ± 0.61 | 0.075 |
| FEV1, L | 3.36 ± 0.44 | 3.28 ± 0.53 | 0.188 | 2.47 ± 0.42 | 2.31 ± 0.47 | 0.125 |
| FEV1/FVC, (% pred) | 100 ± 6.0 | 101 ± 6.4 | 0.285 | 101 ± 7.4 | 103 ± 6.9 | 0.231 |
| PEF, L/s | 8.36 ± 1.33 | 8.12 ± 1.60 | 0.266 | 6.02 ± 1.10 | 5.78 ± 0.97 | 0.350 |
| MEF75, L/s | 7.16 ± 1.38 | 6.86 ± 1.40 | 0.132 | 5.39 ± 1.27 | 5.31 ± 1.15 | 0.785 |
| MEF50, L/s | 4.02 ± 0.96 | 3.80 ± 1.13 | 0.158 | 3.29 ± 1.13 | 3.04 ± 0.84 | 0.300 |
| MEF25, L/s | 1.43 ± 0.52 | 1.35 ± 0.56 | 0.138 | 1.12 ± 0.61 | 0.98 ± 0.40 | 0.275 |
| MEF25–75, L/s | 3.30 ± 0.87 | 3.13 ± 0.98 | 0.325 | 2.59 ± 0.97 | 2.40 ± 0.71 | 0.355 |
| ERV, L | 1.56 ± 0.55 | 1.26 ± 0.53 | <0.001 | 1.09 ± 0.53 | 0.83 ± 0.40 | 0.022 |
| FRC, L | 3.73 ± 0.57 | 3.40 ± 0.62 | <0.001 | 2.87 ± 0.57 | 2.60 ± 0.47 | 0.037 |
| TLC, L | 6.24 ± 0.61 | 6.08 ± 0.74 | 0.103 | 4.70 ± 0.48 | 4.50 ± 0.62 | 0.140 |
| RV, L | 2.17 ± 0.38 | 2.15 ± 0.41 | 0.740 | 1.78 ± 0.32 | 1.77 ± 0.32 | 0.953 |
| IC, L | 2.51 ± 0.55 | 2.68 ± 0.56 | 0.041 | 1.83 ± 0.39 | 1.90 ± 0.45 | 0.494 |
| VC, L | 4.07 ± 0.56 | 3.93 ± 0.64 | 0.124 | 2.92 ± 0.45 | 2.73 ± 0.53 | 0.102 |
| ERV/TLC, % | 25.0 ± 8.2 | 20.5 ± 7.8 | <0.001 | 23.0 ± 9.4 | 18.4 ± 8.4 | 0.035 |
| FRC/TLC, % | 59.8 ± 7.5 | 55.9 ± 7.4 | <0.001 | 61.0 ± 8.0 | 57.2 ± 7.8 | 0.046 |
| RV/TLC, % | 34.8 ± 5.6 | 35.5 ± 5.8 | 0.425 | 37.9 ± 6.3 | 39.5 ± 6.6 | 0.275 |
| I C/TLC, % | 40.2 ± 7.5 | 44.0 ± 7.6 | 0.001 | 39.1 ± 7.9 | 42.1 ± 8.0 | 0.121 |
| VC/TLC, % | 65.6 ± 5.6 | 64.6 ± 5.7 | 0.501 | 62.2 ± 6.3 | 60.5 ± 6.6 | 0.274 |
| AI, events/h | 0.2(0–4.4) | 20.0(0–101.7) | <0.001† | 0(0–2.7) | 2.6(0–57.6) | <0.001† |
| HI, events/h | 2.4(0–9.2) | 9.7(0.1–40.9) | <0.001† | 2.7(0–6.5) | 20.0(2.8–86) | <0.001† |
| AHI, events/h | 3.6(0–10) | 30.8(10.4–102.1) | <0.001† | 3.2(0–6.5) | 23.6(5.4–86.2) | <0.001† |
Abbreviations: BMI body mass index, FVC forced vital capacity, FEV 1 forced expiratory volume in 1 s, FEV 1 /FVC(%, pred) ratio of FEV1 to FVC (ratio of the value to the predicted FEV1/FVC), PEF peak expiratory flow, MEF 75,50,25 maximal expiratory flow at 75 %, 50 %, and 25 % of FVC, ERV expiratory reserve volume, FRC functional residual capacity, RV residual volume, TLC total lung capacity, IC inspiratory capacity, VC vital capacity, ERV/TLC ratio of ERV to TLC, AI apnea index, HI hypopnea index, AHI apnea + hypopnea index. Normally distributed data are expressed as mean ± SD; AI, HI and AHI are expressed as median (range). Comparison was made between the groups using the Independent-Samples t-test or t’-test, when data for variables showed a normal distribution and homogeneity or inhomogeneity of variances, otherwise, Wilcoxon test was used. A p-value below 0.05 was considered to be significant. † represents Mann–Whitney-Wilcoxon test