TABLE 2.
Biomarker models for insulin resistance
| ORa | SD | Accuracy | |
| Model 1: lipoprotein profile prediagnosis | |||
| Moiety | |||
| HDL total | −31.1 | 8.154 | 88% |
| HDL large particles | −13.2 | 2.817 | |
| HDL cholesterol | −23.9 | 5.189 | |
| IDL | −7.5 | 30.393 | |
| Model 2: lipoprotein profile at diagnosis | |||
| Moiety | |||
| HDL total | −88.1 | 11.12 | 100% |
| HDL small particles | −100 | 2.15 | |
| IDL | 918.6 | 29.652 | |
| TAGs | 7,116.8 | 80.06 | |
| Model 3: DAG composition at diagnosis | |||
| Fatty acid | |||
| C16:1 | −61.4 | 0.569 | 100% |
| C18:2(n-6) | 169.4 | 5.274 | |
| C18:3(n-3) | −9.7 | 0.181 | |
| C20:1(n-7) | −35.8 | 0.19 | |
| Model 4: lipid metabolism index at diagnosis | |||
| Moiety | |||
| PL C18:0 | 65.2 | 237.8 | 100% |
| PL C18:3(n-6) | 21.4 | 2.5 | |
| TAG C14:0 | 1.0 | 3.4 | |
| HDL total | −43.3 | 4.4 | |
| HDL large particles | −13.5 | 1.9 | |
| LDL large particles | 15.8 | 126.0 | |
| TAGs | 42.3 | 80.1 | |
| Adiponectin HMW | −1.3 | 128.5 | |
a
OR, OR for change in 1 SD.