Table 1.
Mean number and range of hospitalized varicella cases per year, mean age-specific incidence, and mean age-adjusted incidence of varicella hospitalizations per 100,000 (HI) before varicella vaccination (pre-vaccination, 1995–2003) and after the introduction of varicella vaccination (post-vaccination, 2005–2012) in Germany (*** P < 0.05 was regarded as significant)
| Age in years | pre-vaccination (1995–2003) | post-vaccination (2005–2012) | |||
|---|---|---|---|---|---|
| Mean number of cases per year (range: min; max) | Mean HI (cases per 100,000) | Mean number of cases per year (range: min; max) | Mean HI (cases per 100,000) | p-value for mean HI*** P < 0.05 | |
| <1 | 327.8 (232; 479) | 42.56 | 112.3 (44; 220) | 16.47 | *** |
| 1–4 | 691.9 (612; 747) | 21.76 | 231.1 (71; 569) | 8.15 | *** |
| 5–9 | 264.0 (206; 320) | 6.08 | 143.8 (66; 237) | 3.79 | *** |
| 10—14 | 64.2 (46; 84) | 1.40 | 47.3 (38; 56) | 1.18 | p = 0.06 |
| 15—19 | 58.0 (34; 69) | 1.27 | 50.8 (39; 65) | 1.13 | p = 0.15 |
| 20—49 | 450.4 (395; 520) | 1.26 | 392.4 (348; 469) | 1.15 | p = 0.09 |
| 50 and older | 88.7 (45; 143) | 0.30 | 193.4 (146; 265) | 0.60 | *** |
| total (age adjusted) | 1948.8 (1810; 2084) | 3.30 | 1171.0 (865; 1751) | 1.86 | *** |