Skip to main content
. 2015 Apr 15;11(6):1368–1386. doi: 10.1080/21645515.2015.1026495

Table 2:

HER-2 & IGF-1R

Peptide Abs Proliferation % inhibition BT474/ JIMT-1 Phosphorylation % Inhibition BT474/ JIMT-1 ADCC % Lysis (100:1) JIMT-1 Apoptosis Luminescense x106 BT474/ JIMT-1 Invasion Assay JIMT-1 cells invaded
α-HER-2 (597) 35/8 pHER-2; HER-2: 10/5 IGF-1R:10/15 12 14/3 580
α-IGF-1R (56) 12/25 p-IGF-1R; HER-2: 7/7 IGF-1R: 20/45 40 4/14 550
α-HER-2 597 + α-IGF-1R(56) 40/45;P<0.003 pHER-2; 10/25; P<0.05; p-IGF-1R; 25/55; P<0.005 70; P<0.001 15/17; P<0.001 400; P<0.05