Skip to main content
. 2015 Apr 15;11(6):1368–1386. doi: 10.1080/21645515.2015.1026495

Table 3:

HER-1 & IGF-1R

Peptide mimics or Peptide Abs Proliferation % inhibition JIMT-1 /BxPC3 Peptide Mimics Phosphorylation % Inhibition JIMT-1 /BxPC3 Peptide Mimics ADCC %Lysis(100:1) JIMT-1 Peptide Abs Apoptosis Luminescense x106 JIMT-1 /BxPC3 Peptide Abs Invasion Assay JIMT-1 cells invaded Peptide Abs
HER-1 (418) 25/50 P<0.005 p-HER-1; HER-1: 20/18 IGF-1R: 18/20 20 P<0.001 4/4 P<0.001 800
IGF-1R(56) 50/25 P<0.005 p-IGF-1R; HER-1:30/25 IGF-1R: 30/30 50 P<0.001 8/8 P<0.001 800
HER-1(418) + IGF-1R (56) 75/75 P<0.001 p-HER-1; HER-1: 50/30; P<001 p-IGF-1R: IGF-1R: 40/55; P<005 70 P<0.001 12/15 P<0.001 500; P<0.05