Table 4:

HER-3 & IGF-1R

Peptide mimics /peptide Abs	Proliferation % inhibition JIMT-1 /BxPC3 peptide mimics	Phosphorylation % Inhibition JIMT-1 /BxPC3 peptide mimics	ADCC %Lysis(100:1) JIMT-1 peptide Abs	Apoptosis Luminescense x106 JIMT-1 peptide Abs
HER-3	10/10	p-HER3 HER-3: 40/42; IGF-1R: 17/18	10	10
IGF-1R	40/20	p-IGF-1R: HER-3: 22/22 IGF-1R: 20/22	40	12
HER-3 + IGF-1R	55/30; P<0.04	p-HER-3; 55/65; P<0.01 p-IGF-1R; 45/ 30; P<0.02	70; P<0.037	15; P<0.002