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HER-3 & HER-2
| peptide Abs | Proliferation % inhibition BT474 /JIMT-1 | Phosphorylation %Inhibition BT474 /JIMT-1 | ADCC % Lysis BT474 | Apoptosis Luminescense x104 BT474 |
|---|---|---|---|---|
| HER-2-(597) | 20/10 | p-HER-3 HER-3: 25/15; HER-2: 22/12 | 12 | 12 |
| HER-3 (461) | 35/10 | p-HER-2 HER-3: 20/5; HER-2: 40/10 | 10 | 4 |
| HER-2 + HER-3 | 50/18; P<0.02 | pHER-3; 35/17; P<0.05 pHER-2; 65/18; P<0.02 | 20; P<0.05 | 16 |
