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. 2014 Aug 12;11(1):124–132. doi: 10.4161/hv.34366

Table 1. TBA and ELISA unit data from mice immunized with either Pfs25MF3E or Pfs25-FhCMB.

Study Day 42 Study Day 168
Vaccine candidate Dose (µg) ELISA units Prevalence a Intensity b % reduction c p-value d ELISA units Prevalence a Intensity b % reduction c p-value d
Pfs25MF3E 5 5835 5 0.1 (0–1) 99 < 0.001 4346 45 1.2 (0–11) 96 < 0.001
Pfs25MF3E 1 4696 65 1.2 (0–4) 92 < 0.001 3120 85 8.7 (0–21) 68 < 0.05
Pfs25MF3E 0.2 3318 40 0.9 (0–3) 94 < 0.001 4926 75 2.3 (0–6) 92 < 0.001
Pfs25-FhCMB 5 7404 5 0.1 (0–1) 99 < 0.001 7180 10 0.2 (0–2) 99 < 0.001
Pfs25-FhCMB 1 14923 10 0.1 (0–1) 99 < 0.001 12124 60 1.3 (0–4) 95 < 0.001
Pfs25-FhCMB 0.2 4909 10 0.1 (0–1) 99 < 0.001 4180 85 7.7 (0–29) 72 < 0.05
LicKM only 2.5 22 80 14.2 (0–56) - - 84 100 27.6 (1–56) - -

a The proportion (percentage) of mosquitoes infected; bArithmetic mean of oocysts per feeder (the range of oocysts); c% reduction = ((mean control oocyst - mean test oocyst) / mean control oocyst)*100; dSignificance when compared with the LicKM only group.