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. 2015 Apr 1;11(4):970–982. doi: 10.1080/21645515.2015.1010859

Table 7.

GMTs in subjects with ≥4 -fold rises in antibody titers after 2 doses of H2N2 LAIV

After 2 doses, Day 56 After 2 doses, Day 112
Reverse GMTs Reverse GMTs
Assay n Day 0 Day 56 GMT rise n Day 0 Day 112 GMT rise
HAI: serum Ab 9 2.5 13.6 5.4 15 2.5 13.2 5.3
MN: serum Ab 12 5.0 20.0 4.0 12 5.0 20.0 4.0
ELISA: serum IgA 14 8.8 41.0 4.7 12 9.0 47.9 5.3
ELISA: nasal IgA 13 1.9 12.9 6.8 n/a n/a n/a n/a
ELISA: salivary IgA 12 3.6 14.3 4.0 n/a n/a n/a n/a

GMT – geometric mean titer; HAI – hemagglutination inhibition assay; MN – microneutralization; ELISA - Enzyme-linked immunosorbent assay; Ab – antibody; n/a – not applicable (nasal swab and saliva samples were not collected at Day 112).