Table 7.
After 2 doses, Day 56 | After 2 doses, Day 112 | |||||||
---|---|---|---|---|---|---|---|---|
Reverse GMTs | Reverse GMTs | |||||||
Assay | n | Day 0 | Day 56 | GMT rise | n | Day 0 | Day 112 | GMT rise |
HAI: serum Ab | 9 | 2.5 | 13.6 | 5.4 | 15 | 2.5 | 13.2 | 5.3 |
MN: serum Ab | 12 | 5.0 | 20.0 | 4.0 | 12 | 5.0 | 20.0 | 4.0 |
ELISA: serum IgA | 14 | 8.8 | 41.0 | 4.7 | 12 | 9.0 | 47.9 | 5.3 |
ELISA: nasal IgA | 13 | 1.9 | 12.9 | 6.8 | n/a | n/a | n/a | n/a |
ELISA: salivary IgA | 12 | 3.6 | 14.3 | 4.0 | n/a | n/a | n/a | n/a |
GMT – geometric mean titer; HAI – hemagglutination inhibition assay; MN – microneutralization; ELISA - Enzyme-linked immunosorbent assay; Ab – antibody; n/a – not applicable (nasal swab and saliva samples were not collected at Day 112).