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. 2015 Apr 6;11(6):1540–1556. doi: 10.1080/21645515.2015.1026500

Figure 4.

Figure 4.

IFNγ and CD8+ T-cell proliferation responses to Fp9, Fp14, and Hp15 peptide epitopes. Peptide pool Fp14 consists of 4 overlapping 13–15mer peptides spanning the amino- to carboxyl-terminus (Fp14–1, Fp14–2, Fp14–3, Fp14–4), while pools Hp15 (Hp15–1, Hp15–2, Hp15–3) and Fp9 (Fp9–1, Fp9–2, Fp9–3) each consist of 3 overlapping 13–15mer peptides. IFNγ responses to individual Fp14 peptides (A; n=9 ), Hp15 peptides (B; n=9 ) and CD8+ T-cell proliferation responses to individual Fp9 peptides (C; n=7 ) are shown along with responses to their corresponding peptide pools. Only responders to pools Fp14 (A), Hp15 (B), and Fp9 (C) were tested. The responders consisted of long-term survivors (LTS) without ART (LTS; black bar); recently diagnosed subjects (<1 year) with short-term infection without ART (ST; gray bar); and those on ART with various duration of infection (ART+, red bar). Each bar with (*) in panels A and B are from the same 3 LTS.