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. 2015 Jan 22;11(2):421–427. doi: 10.4161/21645515.2014.988549

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Figure 3. — Cytokine responses in mice immunized with different pertussis vaccines. Seven days after the second immunization, spleen cells were prepared from 5 mice from each group. The cytokines were determined by ELISA. Results are the mean responses for 5 mice per group. *indicates a statistically significant difference (P < 0.05) compared with co-purified (S2 and S3) and purified (S4) APV groups. # indicates a statistically significant difference (P < 0.05) compared with purified (S4) APV groups.