Table 1.
MAb | Group | Subtype | Challenge | Model | Reference |
---|---|---|---|---|---|
C179 | 1 | H1, H2, H5 | H1N1/H5N2 | Mice | 105,106 |
CR6261 | 1 | H1, H2, H5, H6, H8, H9 | H1N1/H5N1 | Mice | 107,108 |
F10 | 1 | H1, H2, H5, H6, H11, H13, H16, H9 | H1N1/H5N1 | Mice | 109 |
12D1 | 2 | H3 | H3N2 | Mice | 110 |
CR8020 | 2 | H3, H7, H10 | H3N2/H7N7 | Mice | 190 |
FI6v3 | 1 and 2 | All | H1N1 | Mice, ferret | 111 |
CR911* | 1 and 2 | All | H1N1/H3N2 | Mice | 112 |
Also neutralizes influenza B virus and protects a model from challenge with lethal influenza B virus.