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. 2015 May 27;11(5):1129–1139. doi: 10.1080/21645515.2015.1009343

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Figure 4. — Comparable antigenicity of different HEV p239 VLP samples was determined using an SPR method with 6 different mAbs. (A) The RU ratio for p239 VLPs (△RU_Ag) binding to a given amount of captured mAbs (△RU_Ab) was tracked (rRU=△RU_Ag/△RU_Ab). The relative antigenicity was calculated by normalizing the rRU value of each sample (Samples a, c and c₀) to the native p239 VLP (Sample a). (B) The key conformational and linear epitopes on the surface of HEV p239 VLPs recognized by different mAbs are illustrated.