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Figure 1. Mouse skin APCs shape adaptive immune responses. APC populations of the epidermis and dermis have high propensity for modulation of adaptive immune responses. This figure summarizes published works describing interaction between skin APC and T cell in skin and draining lymph node at steady-state or during inflammatory responses. InfDC, inflammatory dendritic cell; LC, Langerhans cell; TH, T helper; TREG, regulatory T cell.
