Table 5. Differential expression results for all comparison groups corresponding to four cytokine genes that were selected for further study.

Genes were selected based on being (1) members of the GO:0008009~chemokine activity ontological category, which was significantly over-represented among genes differentially expressed in response to vitamin D treatment in both fatal asthma- and non-asthma-derived ASM, that were (2) differentially expressed in fatal asthma-derived vs. non-asthma-derived ASM at baseline. FPKM = fragments per kilobase of transcript per million mapped reads.

						Fatal Asthma vs. Non-Asthma at Baseline		Non-Asthma Vitamin D vs. Baseline		Fatal Asthma Vitamin D vs. Baseline
Gene	Locus	Mean FPKM Non-Asthma Baseline	Mean FPKM Fatal Asthma Baseline	Mean FPKM Non-Asthma Vitamin D	Mean FPKM Fatal Asthma Vitamin D	Log2[Fold Change]	Q-value	Log2[Fold Change]	Q-value	Log2[Fold Change]	Q-value
CCL2	chr17:32582295–32584220	166.2	300.3	51.1	65.1	0.85	1.9E-03	-1.70	1.9E-03	-2.21	1.9E-03
CCL13	chr17:32683470–32685629	1.31	5.62	0.42	1.49	2.10	1.9E-03	-1.63	2.9E-02	-1.91	6.3E-03
CXCL12	chr10:44865604–44880545	681.0	294.2	912.2	1009.5	-1.21	1.3E-02	0.42	0.61	1.78	1.9E-03
IL8	chr4:74606222–74609433	0.87	4.31	0.09	0.16	2.31	1.9E-03	-3.22	1.9E-03	-4.79	1.9E-03