Table 2. Clinical parameters of the patients in the HVHF and IHD groups before and after treatment.
| Parameter | Before treatment | P value | After treatment | P value | Change after treatment | P value | |||
|---|---|---|---|---|---|---|---|---|---|
| HVHF group | IHD group | HVHF group | IHD group | HVHF group | IHD group | ||||
| APACHE II score | 21.33 ± 3.14 | 21.27 ± 3.62 | 0.953 | 14.24 ± 2.10** | 17.07 ± 2.52** | 0.002 | 7.09 ± 2.62 | 4.20 ± 1.69 | 0.0003 |
| MOD score | 12.29 ± 2.51 | 11.80 ± 2.37 | 0.562 | 8.00 ± 1.70** | 9.53 ± 2.33 | 0.047 | 4.29 ± 1.08 | 2.27 ± 1.07 | < 0.0001 |
| PaO2/FiO2 (mmHg) | 286.55 ± 120.10 | 291.28 ± 125.59 | 0.910 | 407.97 ± 75.48** | 390.76 ± 120.81* | 0.634 | |||
| MAP (mmHg) | 60.10 ± 5.22 | 59.07 ± 5.19 | 0.563 | 77.05 ± 10.42** | 75.33 ± 13.82** | 0.700 | |||
| PT (s) | 17.33 ± 5.31 | 17.47 ± 4.42 | 0.937 | 12.38 ± 4.80** | 12.87 ± 5.38* | 0.795 | |||
| PLT (×109/L) | 62.24 ± 14.22 | 63.67 ± 18.06 | 0.792 | 158.57 ± 15.16** | 153.33 ± 17.03** | 0.386 | |||
| HB (g/dL) | 7.395 ± 1.087 | 7.373 ± 1.216 | 0.955 | 9.029 ± 1.492** | 8.333 ± 1.115* | 0.181 | |||
| Myoglobin (ng/mL) | 1254.9 ± 186.2 | 1177.3 ± 162.5 | 0.203 | 250.7 ± 41.8** | 683.1 ± 66.4 | < 0.001 | |||
| CK-MB (U/L) | 127.43 ± 25.43 | 128.87 ± 23.57 | 0.864 | 50.10 ± 18.97** | 98.93 ± 29.07 | < 0.001 | |||
| AST (U/L) | 861.29 ± 60.40 | 884.33 ± 53.67 | 0.246 | 52.62 ± 10.65** | 224.73 ± 15.11* | < 0.001 | |||
| LDH (U/L) | 6011.7 ± 139.8 | 5967.2 ± 154.8 | 0.375 | 288.7 ± 16.2** | 1486.2 ± 36.1* | < 0.001 | |||
| TBI (μmol/L) | 78.95 ± 19.90 | 88.13 ± 19.06 | 0.174 | 37.67 ± 11.53* | 66.13 ± 16.08 | < 0.001 | |||
| DBI (μmol/L) | 25.00 ± 12.05 | 19.53 ± 10.09 | 0.161 | 11.95 ± 3.46* | 19.47 ± 6.92 | < 0.001 | |||
| IBI (μmol/L) | 53.95 ± 18.42 | 64.73 ± 17.04 | 0.083 | 25.95 ± 9.48* | 46.67 ± 11.58 | < 0.001 | |||
| BUN (mmol/L) | 30.48 ± 8.12 | 31.33 ± 9.52 | 0.773 | 12.29 ± 4.62** | 14.20 ± 3.39** | 0.228 | |||
| Scr (μmol/L) | 314.05 ± 48.73 | 295.53 ± 39.39 | 0.233 | 189.00 ± 29.85* | 274.53 ± 19.45 | < 0.001 |
Note: Data are presented as the mean ± standard deviation.
* P < 0.05
** P < 0.01 vs. that before treatment.
APACHE score, Acute Physiology and Chronic Health Evaluation II; AST, aspartate aminotransferase level; BUN, blood urea nitrogen level; CK-MB, creatine kinase-MB level; DBI, direct bilirubin index; HB, hemoglobin level; HVHF, high-volume hemofiltration; IBI, indirect bilirubin index; IHD, intermittent hemodialysis; LDH, lactate dehydrogenase level; MAP, mean arterial pressure; MOD score, multiple organ dysfunction score; PLT, platelet count; PT, prothrombin time; Scr, serum creatinine level; TBI, total bilirubin index.