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. 2015 Jul 24;10(7):e0133391. doi: 10.1371/journal.pone.0133391

Fig 7. Rosiglitazone attenuates hypoxia-induced TGF-β1 expression.

Fig 7

(A) Mice were exposed to normoxia or hypoxia for 3 weeks and treated with vehicle or RSG during the last 10 days, and (A) TGF-β1 mRNA was quantified. (B) HPASMC pre-treated with TGF-β1 neutralizing antibodies (1 μg/ml) for four hours were placed into a hypoxia chamber for 48 hours and miR-21 expression was quantified. Each bar represents mean ± SEM (A) TGF-β1 mRNA or (B) miR-21 levels. *P< 0.05 vs Normoxia (-), #P< 0.01 vs Hypoxia (-) (n = 5–7)