Table 1. Allele and overall genotype association of rs71305152 with glioma.
Cohort | Subject | Allele | Genotype | |||||||
---|---|---|---|---|---|---|---|---|---|---|
n (M/F Ratio b ) | I % (n) | D % (n) | OR c | 95% CI d | P e | II % (n) | ID % (n) | DD % (n) | P f | |
Glioma | 350 (1.54) | 33.57 (235) | 66.43 (465) | 15.14 (53) | 36.86 (129) | 48.00 (168) | ||||
Non-glioma a | 354 (1.51) | 35.45 (251) | 64.55 (457) | 0.920 | 0.739–1.146 | 0.458 | 12.71 (45) | 45.48 (161) | 41.81 (148) | 0.066 |
Control | 463(1.02) | 34.77 (322) | 65.23 (604) | 0.948 | 0.770–1.166 | 0.613 | 11.45 (53) | 46.65 (216) | 41.90 (194) | 0.016 |
a Non-glioma cohort includes lung cancer, leukemia and lymphoma cohorts;
b M/F Ratio is the ratio of successfully genotyped male to female;
c OR is the odds ratio;
d 95% CI is 95% confidence interval;
e P values pertain to allele frequency difference between glioma cohort and either non-glioma cancer cohort or control cohort;
f P values pertain to overall genotype frequency difference between glioma cohort and either non-glioma cancer cohort or control cohort;
P value of less than 0.05 is highlighted.