Table 1.

Enriched KEGG pathways of candidate genes in the BC dataset

Enriched KEGG pathway	Number of genes	Adjusted P-value*
dmGWAS
Metabolic pathway	11	4.40 × 10−5
EW_dmGWAS
Pathways in cancer	10	8.22 × 10−7
RIG-I-like receptor signaling pathway	6	1.11 × 10−6
Neurotrophin signaling pathway	7	1.71 × 10−6
Tight junction	7	2.23 × 10−6
Hepatitis C	7	2.48 × 10−6
ErbB signaling pathway	6	3.78 × 10−6
Endocytosis	7	3.80 × 10−5
Adherens junction	5	4.08 × 10−5
GnRH signaling pathway	5	2.00 × 10−4
Leukocyte transendothelial migration	5	4.00 × 10−4
Focal adhesion	6	5.00 × 10−4
Jak-STAT signaling pathway	5	1.50 × 10−3
Calcium signaling pathway	5	3.00 × 10−3
Chemokine signaling pathway	5	4.50 × 10−3
GBR
Regulation of actin cytoskeleton	6	7.40 × 10−5
Neurotrophin signaling pathway	5	7.40 × 10−5
Axon guidance	5	7.40 × 10−5
Pathways in cancer	6	5.00 × 10−4
MetaRanker 2.0
Purine metabolism	5	3.00 × 10−4
Pathways in cancer	6	6.00 × 10−4
Metabolic pathways	9	6..40 × 10−3

*P-values were adjusted by Bonferroni correction.