Table 4.
Crude and adjusted associations of plaque burden and angiogenesis inhibitor concentration
| Factor (median [IQR]) | Unadjusted β (95 % CI) | P value | Adjusted β (95 % CI) | P value |
|---|---|---|---|---|
| Endostatin (per 100 ng/mL) | −0.16 (−0.04, 0.13) | 0.28 | 0.00 (−0.03, 0.036) | 0.97 |
| ADMA (per 0.1 μmol/L) | 0.02 (−0.03, 0.08) | 0.39 | 0.03 (−0.02, 0.09) | 0.25 |
| Thrombospondin-2 (per 100 pg/mL) | 0.02 (0.00, 0.01) | 0.37 | 0.00 (0.00, 0.01) | 0.62 |
| Endoglin (per 1 ng/mL) | −0.01 (−0.07, 0.05) | 0.81 | 0.01 (−0.05, 0.07) | 0.81 |
| Angiopoietin-2 (per 1 ng/mL) | 0.00 (−0.03, 0.02) | 0.69 | 0.01 (–0.02, 0.04) | 0.44 |
Association of inhibitor level with log transformed plaque burden