Fig. 4.

a Cell proliferation assay. Proliferation rate of AZ521-con and AZ521-kd cells as evaluated with the BrdU assay at 12, 24 and 48 h post cisplatin treatment. Untreated cells served as experimental control. Results are representative of two independent experiments and error bars indicate standard deviations. b Clonogenic survival assay. The colony formation ability of AZ521-con and AZ521-kd cells were measured after cisplatin treatment. Untreated cells served as experimental control. Results are representative of two independent experiments and error bars indicate standard deviations