Table 2.
Unadjusted incidence rates of venous thromboembolic events, before and after STS diagnosis
| n = 3,480 STSa patients | Incidence 12 months before STS diagnosis | Incidence 12 months after STS diagnosis |
|---|---|---|
| DVTa | ||
| n/person-yearsb | 137/3,418 | 367/2,468 |
| Rate/1,000c | 40.1 (33.7–164.7) | 148.7 (133.9–164.7) |
| Rate ratio (after vs. before)d | – | 3.7 (3.0–4.5) |
| PEa | ||
| n/person-yearsb | 34/3,463 | 105/2,589 |
| Rate/1,000c | 9.8 (6.8–49.1) | 40.6 (33.2–49.1) |
| Rate ratio (after vs. before)d | – | 4.1 (2.8–6.1) |
| OTEa | ||
| n/person-yearsb | 82/3,438 | 106/2,590 |
| Rate/1,000c | 23.9 (19.0–49.5) | 40.9 (33.5–49.5) |
| Rate ratio (after vs. before)d | – | 1.7 (1.3–2.3) |
Rate ratios are highlighted in italics.
a VTE venous thromboembolic events, STS soft tissue sarcoma, DVT deep vein thrombosis, PE pulmonary embolism, OTE other thromboembolic event. OTE category includes the following diagnoses: central retinal vein occlusion, venous tributary (branch) occlusion, nonpyogenic thrombosis of intracranial venous sinus, phlebitis/thrombophlebitis of superficial vessels of lower extremities, phlebitis/thrombophlebitis of superficial veins of upper extremities, phlebitis/thrombophlebitis of other sites, gout with other specified manifestations, Budd–Chiari syndrome, and venous embolism/thrombosis of renal vein.
b n number of VTE events, p-y person-years.
cRates are per 1,000 person-years and are unadjusted. Age adjustment is unnecessary as these rates are intentionally representative of the older subpopulation (ages 65+) of STS patients. Only first VTE counted in rate estimates.
dRate ratios are unadjusted.