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. 2015 Jun 15;145(4):543–557. doi: 10.1111/imm.12471

Figure 4.

Figure 4

Increased accumulation of KLRG1-high (KLRG1hi) STAT5-expressing effector T cells (Teff-STAT5CA) in the absence of CDK2NA expression. Wild-type (WT) or CDK2NA−/− CD8 Teff-STAT5CA were injected in Rag-1−/− B10.D2 mice. Thirty days later, CD8 T cells recovered from pooled lymph nodes and spleens were analysed. (a–c) The representation of the transferred CD8 T cells in the spleen is shown in dot plots of CD8 expression versus SSC-A (left dot plots). KLRG1 expression versus FSC-A among gated CD8+ T cells is shown (right dot plots) and the % of KLRG1+ cells is reported. (b) % and absolute numbers of KLRG1+ cells are reported. (c) the MFI for KLRG1 staining is reported. (d, e) Cells were stained for CD8 and activation markers: KLRG1 versus CD127 (left) and CD25 (right) plots are shown. Naive CD8 T cells are included as control. Percent positive cells are reported. Data are representative of four independent experiments. The MFI for CD25 staining on KLRG1+ cells is reported in (e).