Table 2.

Effect sizes and Outcome Measures for Treatment Efficacy, Treatment Response and Symptom/Diagnostic Remission Across Included Trials

	Treatment Efficacy Measure	Effect size (Hedges’ g)	Treatment Response Measure	Relative Risk of Treatment Resposne	Symptom /Diagnostic Remission Measure	Relative Risk of Symptom/Diagnostic Remission
CBT Trials
Barrett et al. 2004	CYBOCS	2.82	25% CYBOCS Reduction	19.00	ADIS-P	43.00
POTS, 2004a	CYBOCS	1.06	25% CYBOCS Reduction	2.50	CYBOCS ≤10	15.00
Bolton & Perrin, 2007	CYBOCS	1.02	25% CYBOCS Reduction	13.00	CYBOCS ≤14	2.50
Freeman et al. 2008	CYBOCS	0.49	CGI-I	1.25	CYBOCS ≤12	2.50
Williams et al. 2010	CYBOCS	1.31	25% CYBOCS Reduction	3.18	CYBOCS ≤14	2.73
Bolton et al. 2011	CYBOCS	1.45	25% CYBOCS Reduction	3.87	ADIS-C/P	7.33
Piacentini et al. 2011	CYBOCS	0.38	CGI-I	2.10	CYBOCS ≤10	2.54
Storch et al. 2011	CYBOCS	1.15	CGI-I	6.09	CYBOCS ≤10	4.22
Lewin et al. 2014	CYBOCS	1.62	CGI-I	9.06	CYBOCS ≤12	17.50
Freeman et al. 2014	CYBOCS	1.18	CGI-I	1.76	CYBOCS ≤14	1.94
SRI Trials
Flament et al. 1985b	NIMH-GOCS	0.78	NA	---	NA	---
Leonard et al. 1989b	NIMH-GOCS	0.78	NA	---	NA	---
March et al. 1990c	CYBOCS	0.51	NA	---	NA	---
DeVeaugh-Geiss et al. 1992	CYBOCS	0.73	CGI-I	3.56	NA	---
Riddle et al. 1992	CYBOCS	0.78	NA	---	NA	---
March et al. 1998	CYBOCS	0.62	CGI-I	1.61	NA	---
Geller et al. 2001	CYBOCS	0.44	CGI-I	2.93	40% CYBOCS Reduction	1.97
Riddle et al. 2001	CYBOCS	0.31	CGI-I	1.88	NA	---
Liebowietz et al. 2002	CYBOCS	0.24	CGI-I	1.80	CYBOCS ≤14	1.44
Geller et al. 2004	CYBOCS	0.40	CGI-I	1.38	NA	---
POTS, 2004a	CYBOCS	0.44	25% CYBOCS Reduction	2.13	CYBOCS ≤10	11.00

^aplacebo group used in both,

^bused a cross-over trial design

NOTE: CY-BOCS = Children’s Yale-Brown Obsessive-Compulsive Scale, NIMH-GOCS = National Institute of Mental Health Global Obsessive Compulsive Disorder Scale, NA = Not Available/Applicable, CGI-I = Clinical Global Impression of Improvement, ADIS-C/P = Anxiety Disorder Interview Schedule-Child and Parent report