Table 1.
Baseline demographic and alcohol drinking characteristics of the study cohort
| Demographic and clinical characterstics | Non excessive drinkers/Controls (n = 210) | Excessive drinkers (n =272) | p-value |
|---|---|---|---|
|
| |||
| Age (years) | 32.5±8.6 | 39.7±11.8 | <.0001 |
|
| |||
| Male sex, n (%) | 180 (85.7%) | 182 (66.9%) | <.0001 |
|
| |||
| Race, White, n (%) | 168 (80%) | 220 (81%) | 0.22 |
|
| |||
| Marital status (%) | 0.001 | ||
| : Married | 54.3 | 35.3 | |
| : Divorced/separated | 18.1 | 28.3 | |
| : Never married | 19.1 | 27.9 | |
| : Others | 8.5 | 8.5 | |
|
| |||
| BMI (kg/m2) | 29.9±14.31 | 27.9±5.51 | 0.05 |
|
| |||
| AUDIT-C | 4.7±5.67 | 26.9±7.75 | <.0001 |
|
| |||
| Alcohol drinking patterns during the last 30 days from TLFB | |||
| : Total drinks | 13.3±15.3 | 257.7±176.5 | <.0001 |
| : Number of days drinking last 30 days | 4.5±5.3 | 20.1±6.2 | <.0001 |
| : Average drinks per drinking day | 2.5±2.9 | 12.9±7.5 | <.0001 |
| : Average drinks per day | 0.5±0.5 | 8.6±5.8 | <.0001 |
| : Greatest number of drinks in one day | 3.9±3.2 | 18.6±8.92 | <.0001 |
|
| |||
| Laboratory measures | |||
| : Serum AST (U/L) | 26.0±22.0 | 38.9±75.5 | 0.008 |
| : Serum ALT (U/L) | 50.7±1.8 | 36.5±1.9 | <.0001 |
| : Serum GGT (U/L) | 35.6±31.1 | 85.5±126.10 | <.0001 |
| : %Carbohydrate deficient transferrin (%CDT) | 1.9±3.7 | 2.6±1.2 | 0.023 |
| : Mean Corpusular volume (fL) | 89.5±4.3 | 93.4±20.1 | 0.002 |