Table 4.
GEE modelling of outcome trends over time – by age group
Age at baseline < 25 years:
| |||
---|---|---|---|
Outcome | HCV negative aORb (95% CI) p-value |
HCV diagnosed aORb (95% CI) p-value |
Interaction (time*HCV-disclosure group) p-value |
Recenta injection drug use | 0.98 (0.95, 1.02) 0.261 | 0.98 (0.96, 1.00) 0.079 | 0.093 |
Recent syringe borrowing | 0.94 (0.86, 0.99) 0.047 | 0.99 (0.94, 1.04) 0.612 | 0.087 |
Recent receptive sharing - other equipment | 1.04 (0.98, 1.11) 0.169 | 1.00 (0.92, 1.09) 0.911 | 0.301 |
Recent alcohol use | 0.99 (0.97, 1.01) 0.128 | 1.03 (1.01, 1.04) 0.015 | 0.009 |
Age at baseline >= 25 years:
| |||
---|---|---|---|
Outcome | HCV negative aORb (95% CI) p-value |
HCV diagnosed aORb (95% CI) p-value |
Interaction (time*HCV-disclosure group) p-value |
Recenta injection drug use | 0.94 (0.91, 0.96) <0.001 | 0.93 (0.90, 0.97) <0.001 | 0.087 |
Recent syringe borrowing | 0.95 (0.88, 1.01) 0.072 | 0.95 (0.89, 0.99) 0.036 | 0.769 |
Recent receptive sharing - other equipment | 0.97 (0.91, 1.05) 0.401 | 0.96 (0.92, 1.02) 0.109 | 0.606 |
Recent alcohol use | 0.97 (0.91, 1.02) 0.142 | 1.00 (0.99, 1.02) 0.434 | 0.528 |
Recent=past month or past 3-months depending on cohort
aOR = adjusted odds ratio for every 3-month increment post-baseline, adjusted for site, age, sex and baseline outcome value