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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Integr Biol (Camb). 2015 Apr;7(4):454–466. doi: 10.1039/c5ib00052a

Fig. 5. Depth distribution of cell populations with time.

Fig. 5

(A–B) Distributions of the fluorescence intensity in the depth measured from the position of the monolayer. Cells initially seeded on the surface of the gel (RFP+-HUVECs) (A); cells initially distributed within the bulk (GFP+-HUVECs) of the gels (B). BCs were seeded at a density of 1×106 cells/mL; MCs at 250 cells/mm2. Time-points of Day 1 (black), Day 3 (red), Day 5 (blue), and Day 7 (grey) are shown. (C) Comparison of intensity-weighted average depth of invasion in Mono Only, “MO” and Mono + Bulk (medium), “MB (medium)” configurations. (D) Comparison of intensity-weighted average depth of BCs in Bulk Only (medium), “BO (medium)” and Mono + Bulk (medium), “MB (medium)” configurations. Error bar: Standard Deviation. (ns: not significant; *: p < 0.05; **: p < 0.01; ***: p < 0.001)